Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6174890 | European Journal of Obstetrics & Gynecology and Reproductive Biology | 2011 | 5 Pages |
Abstract
Sildenafil citrate reduces the plasma levels of anti-angiogenic factors, sFlt-1 and sEng, in pre-eclamptic (l-NAME induced) Sprague-Dawley rats and may therefore be responsible for the reduction in blood pressure and proteinuria as well as the improved fetal outcomes noted in an earlier study.
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Authors
S.V. Ramesar, I. Mackraj, P. Gathiram, J. Moodley,