Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6177516 | European Urology | 2016 | 12 Pages |
Abstract
High levels of hypoxia-inducible transcription factors (HIF) are particularly important in the clear cell type of kidney cancer, in which they are no longer properly regulated by the von Hippel-Lindau protein. The two HIF-α proteins have opposing effects on tumor evolution.
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Authors
Johannes Schödel, Steffen Grampp, Eamonn R. Maher, Holger Moch, Peter J. Ratcliffe, Paul Russo, David R. Mole,