Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6180544 | Fertility and Sterility | 2012 | 8 Pages |
Abstract
Girls at high risk of developing PCOS display increased adiposity and 17-OHP levels, but are mainly characterized by global insulin resistance and resistance to insulin-induced suppression of lipolysis that were independent of adiposity and 17-OHP levels. Therefore, genetic predisposition to PCOS may be related to early insulin resistance and adipocyte dysfunction.
Keywords
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Authors
Andréanne B.Sc., Marie-Claude Ph.D., David H. M.D., Ph.D., Brigitte M.D., André C. M.D., Judith M.D., Jean-Patrice M.D., M.Sc.,