Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6180840 | Fertility and Sterility | 2011 | 4 Pages |
Abstract
This study was conducted to assess genetic associations with endometriosis in a Puerto Rican population. Statistically significant differences in the allelic frequencies and genotype distribution of genetic variants in lysyl oxidase-like protein 4 (LOXL4) and complement component 3 (C3) were documented in patients with endometriosis-associated infertility versus controls, and in patients with endometriosis versus controls, respectively. In women who have the risk genotype at both single-nucleotide polymorphisms, the estimated risk for endometriosis nearly doubled.
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Authors
Lynnette A. Ph.D., Julie Ph.D., Abigail B.S., Jessica M.P.H., Sonia R.N., JoaquÃn M.D., Idhaliz Ph.D.,