Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6181070 | Fertility and Sterility | 2015 | 10 Pages |
Abstract
The present study showed for the first time that adenomyotic tissues express high levels of myostatin, follistatin, and activin A (growth factors involved in proliferation, apoptosis, and angiogenesis). Increased expression of their receptors supports the hypothesis of a possible local effect of these growth factors in adenomyosis. The augmented expression of ActRIIa, ActRIIb, and follistatin in the endometrium of these patients may play a role in adenomyosis-related infertility.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Obstetrics, Gynecology and Women's Health
Authors
Patrizia Ph.D., Chih-Fen M.D., Felice Ph.D., Lucia Ph.D., Claudia M.D., Tzu-Hao M.D., Joseph S. M.D., Ph.D., Felice M.D.,