Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6181268 | Fertility and Sterility | 2010 | 8 Pages |
Abstract
Trophoblasts and decidua express GnRH-I, GnRH-II, and GnRHR-I mRNA and protein. GnRH-I and -II selectively stimulate hCG production by trophoblast cells without altering the production of select cytokines by trophoblasts or decidua. The role of GnRH-GnRHR signaling at the maternal-fetal interface therefore appears to be limited to the regulation of trophoblast hCG production.
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Authors
Hee Joong M.D., Ph.D., Victoria V. M.D., Joong Shin M.D., Ph.D., Nastaran M.D., Ku Taek M.D., Ph.D., Eric J. M.D., Seth Ph.D., Errol R. M.D., Ph.D.,