| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6182007 | Fertility and Sterility | 2014 | 12 Pages |
Abstract
The discovery of this new class of massive chromosomal rearrangement has deeply modified our understanding on the genesis of complex genomic rearrangements. Data presented in this review support the assumption that chromothripsis could operate in human germlines and during early embryonic development. Chromothripsis might arise more frequently than previously thought in both gametogenesis and early human embryogenesis.
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Authors
Franck Ph.D., Vincent Pharm.D., Jacques M.D., David M.D., Geneviève M.D.,