Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6182439 | Fertility and Sterility | 2012 | 9 Pages |
Abstract
Originally described over three hundred years ago, endometriosis is classically defined by the presence of endometrial glands and stroma in extrauterine locations. Endometriosis is an inflammatory, estrogen-dependent condition associated with pelvic pain and infertility. This work reviews the disease process from theories regarding origin to the molecular basis for disease sequelae. A thorough understanding of the histopathogenesis and pathophysiology of endometriosis is essential to the development of novel diagnostic and treatment approaches for this debilitating condition.
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Authors
Richard O. M.D., M.Sc., Linda C. M.D., Ph.D.,