Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6182747 | Gynecologic Oncology | 2014 | 5 Pages |
Abstract
This large cohort study provides the first evidence that preterm birth is a risk factor for developing sex cord-stromal tumors. Ovarian hyperstimulation in response to high gonadotropin levels in preterm girls could mediate disease risk through the proliferative and steroidogenic effects of FSH and LH on granulosa and theca cells, from which most sex-cord stromal tumors are derived.
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Authors
Weiva Sieh, Kristina Sundquist, Jan Sundquist, Marilyn A. Winkleby, Casey Crump,