Article ID Journal Published Year Pages File Type
6182933 Gynecologic Oncology 2012 10 Pages PDF
Abstract
► Downregulation of miR-130b in 81 cases of ovarian cancer is associated with stages and histological grades. ► Downregulation of miR-130b promotes the development of multidrug- resistant ovarian cancer by targeting CSF-1. ► The silencing of miR-130b may be mediated by DNA methylation. ► miR-130b could potentially be used as a therapeutic target in treatment for multidrug resistant ovarian cancer.
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Related Topics
Health Sciences Medicine and Dentistry Obstetrics, Gynecology and Women's Health
Preview
Epigenetic silencing of miR-130b in ovarian cancer promotes the development of multidrug resistance by targeting colony-stimulating factor 1
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