Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6183006 | Gynecologic Oncology | 2016 | 9 Pages |
Abstract
Overall, our results support that OC platinum resistance was correlated with TMEM88 overexpression regulated through decreased promoter methylation. Our data suggest that TMEM88 functions as an inhibitor of Wnt signaling, contributing to the development of platinum resistance.
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Authors
Maria de Leon, Horacio Cardenas, Edyta Vieth, Robert Emerson, Matthew Segar, Yunlong Liu, Kenneth Nephew, Daniela Matei,