Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6183731 | Gynecologic Oncology | 2013 | 6 Pages |
Abstract
Mathematical modeling of CA-125 kinetics in ROC patients enables understanding of the time-change components during chemotherapy. The contradictory surrogacy of GCIG-defined CA-125 response was confirmed. The modeled CA-125 elimination rate KELIM, potentially assessable in routine, may have promising predictive value regarding PFS. Further validation of this predictive marker is warranted.
Related Topics
Health Sciences
Medicine and Dentistry
Obstetrics, Gynecology and Women's Health
Authors
Benoit You, Olivier Colomban, Mark Heywood, Chee Lee, Margaret Davy, Nicholas Reed, Sandro Pignata, Nenzi Varsellona, Günter Emons, Khalid Rehman, Karina Dahl Steffensen, Alexander Reinthaller, Eric Pujade-Lauraine, Amit Oza,