| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6185148 | Gynecologic Oncology | 2014 | 6 Pages |
Abstract
Combined triage by MAL/miR-124-2 methylation analysis with threshold-80 and HPV16/18 genotyping reaches high CIN3Â + sensitivity with increased specificity to identify women with cervical (pre)cancer among HPV self-sample positive women. The combined strategy is attractive as it is fully molecular and identifies women at the highest risk of cervical (pre)cancer because of strongly elevated methylation levels and/or HPV16/18 positivity.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Obstetrics, Gynecology and Women's Health
Authors
Viola M.J. Verhoef, Daniëlle A.M. Heideman, Folkert J. van Kemenade, Lawrence Rozendaal, Remko P. Bosgraaf, Albertus T. Hesselink, Ruud L.M. Bekkers, Leon F.A.G. Massuger, Renske D.M. Steenbergen, Peter J.F. Snijders, Johannes Berkhof,