Article ID Journal Published Year Pages File Type
6185148 Gynecologic Oncology 2014 6 Pages PDF
Abstract
Combined triage by MAL/miR-124-2 methylation analysis with threshold-80 and HPV16/18 genotyping reaches high CIN3 + sensitivity with increased specificity to identify women with cervical (pre)cancer among HPV self-sample positive women. The combined strategy is attractive as it is fully molecular and identifies women at the highest risk of cervical (pre)cancer because of strongly elevated methylation levels and/or HPV16/18 positivity.
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Health Sciences Medicine and Dentistry Obstetrics, Gynecology and Women's Health
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