| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6185171 | Gynecologic Oncology | 2014 | 10 Pages |
Abstract
This study investigated the expressions of AGTR1 and AGTR2 in epithelial ovarian carcinoma and the therapeutic potential of AGTR modulation with specific antagonist and/or agonist in epithelial ovarian cancer cells. Treatment of AGTR1 antagonist, losartan and/or AGTR2 agonist, CGP42112A synergistically mediated anti-cancer effects including the decrease of cell survival and down-regulation of VEGF.
Keywords
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Authors
Young-Ae Park, Chel Hun Choi, In-Gu Do, Sang Yong Song, Jae Kwan Lee, Young Jae Cho, Jung-Joo Choi, Hye Kyung Jeon, Ji Yoon Ryu, Yoo-Young Lee, Tae-Joong Kim, Duk-Soo Bae, Jeong-Won Lee, Byoung-Gie Kim,