Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6189039 | Reproductive BioMedicine Online | 2014 | 8 Pages |
Abstract
How to improve the implantation rate and clinical outcomes of embryo transfers in patients following IVF is a hot issue in current studies of human assisted reproduction technology. In this study, we aimed to evaluate the effects of quarter zona-pellucida opening by laser assisted hatching (QLAH) on the clinical outcomes following the transfer of vitrified-warmed blastocysts developed from low-grade cleavage-stage embryos in patients with all their high-grade and fair-grade cleavage-stage embryos transferred but who had not become pregnant. Our results showed that the implantation and clinical pregnancy rates were significantly increased after QLAH, suggesting that QLAH may serve as a potential approach for effectively utilizing low-grade cleavage-stage embryos, which are often discarded) and increasing the chances of pregnancy in patients undergoing IVF. However, further multicentre studies on a larger scale should be performed.
Related Topics
Health Sciences
Medicine and Dentistry
Obstetrics, Gynecology and Women's Health
Authors
Cai-Yun Wan, Cheng Song, Liang-Hui Diao, Guan-Gui Li, Zhong-Jian Bao, Xiao-Dong Hu, Hong-Zhan Zhang, Yong Zeng,