Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6193454 | Journal of Thoracic Oncology | 2014 | 9 Pages |
Abstract
Our qRT-PCR assay reliably identifies and distinguishes ALK rearrangements and full-length transcript expression in formalin-fixed, paraffin-embedded material. It is an easy-to-perform, cost-effective, and high-throughput tool for the diagnosis of ALK activation. The expression of full-length ALK transcripts may be relevant for ALK inhibitor therapy in NSCLC.
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Authors
Kim MSc, Heike PhD, Jörg MD, Peter MD, Andreas MD, Martin MD, Godehard MD, Matthias MD, German MD, Claudia PhD,