Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6193697 | Practical Radiation Oncology | 2012 | 6 Pages |
Abstract
There is a higher incidence of HO among the morbidly obese patients despite RT ± indomethacin. RT doses for HO prophylaxis in morbidly obese patients need to be reassessed; also, understanding the signaling pathways in target tissues in obese patients at which adipokines control metabolism may reveal novel therapies. Higher radiation doses ± indomethacin may need to be considered and optimally evaluated in the context of a prospective, randomized clinical trial.
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Authors
Waleed Fouad MD, MSc, PhD, Satya MD, PhD, Rania A. MPH, Zhen MS, Majid A. MD, Matthew MD, Michael C. MD, George MD, Srinivasan MD,