Endophthalmitis prophylaxis in cataract surgery: Overview of current practice patterns in 9 European countries

Data on practice patterns for prophylaxis against infectious postoperative endophthalmitis (IPOE) during cataract surgery in 9 European countries were searched in national registers and reviews of published surveys. Summary reports assessed each nation's IPOE rates, nonantibiotic prophylactic routines, topical and intracameral antibiotic use, and coherence to the European Society of Cataract & Refractive Surgeons (ESCRS) 2007 guidelines. Although the reliability and completeness of available data vary between countries, the results show that IPOE rates differ significantly. Asepsis routines with povidone-iodine and postoperative topical antibiotics are generally adopted. Use of preoperative and perioperative topical antibiotics as well as intracameral cefuroxime varies widely between and within countries. Five years after publication of the ESCRS guidelines, there is no consensus on intracameral cefuroxime use. Major obstacles include legal barriers or persisting controversy about the scientific rationale for systematic intracameral cefuroxime use in some countries and, until recently, lack of a commercially available preparation.Financial DisclosureDr. Pleyer has received research funding from Bundesministerium für Bildung und Forschung and Deutsche Forschungsgemeinschaft and has served as a consultant for Abbott Medical Optics, Inc., Alcon Laboratories, Inc., Allergan, Inc., Bausch & Lomb, Novartis Corp., Santen, Inc., Laboratoires Théa, and Ursapharm Arzneimittel GmbH. Dr. Tassignon has a proprietary interest in the bag-in-the-lens technique and intraocular lenses licensed to Morcher GmbH. No other author has a financial or proprietary interest in any material or method mentioned.