| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6199404 | Ophthalmology | 2016 | 10 Pages |
Abstract
Progressive RNFL thinning determined by GPA and TPA is predictive of detectable functional decline in glaucoma. This finding underscores the significance of detecting progressive RNFL thinning and its relevance to initiate or augment treatment for glaucoma patients. Regulatory authorities may consider progressive RNFL thinning as an outcome measure in clinical trials for evaluation of glaucoma treatment.
Keywords
pointwise linear regressionFDREarly Manifest Glaucoma trialVFICCTtPAEMGTRNFLPLRiOpGPAOctGuided Progression AnalysisOptical coherence tomographydecibelvisual field indexcentral corneal thicknessconfidence intervalIntraocular pressureRetinal nerve fiber layerMean deviationVisual fieldfalse discovery ratehazard ratio
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Authors
Marco PhD, Chen BM, Robert N. MD, Gilda BSc, Vivian BSc, Christopher Kai-Shun MB ChB, MD,