| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6199405 | Ophthalmology | 2016 | 11 Pages |
Abstract
In this study, we confirmed multiple polymorphisms in 8 genes/loci as genetic biomarkers for PACD, among which 3 were identified in a genome-wide association study (COL11A1, PLEKHA7, and PCMTD1-ST18), and 5 were identified in candidate gene studies (HGF, HSP70, MFRP, MMP9, and NOS3).
Keywords
PACGNOS3PACITCaCgiOpHWENOShsp70PACsHardy–Weinberg equilibriumstandard errorperipheral anterior synechiaeconfidence intervalIntraocular pressureprimary angle-closure suspectGenome-wide association studyGWASodds ratioPASNitric oxide synthase 3Newcastle Ottawa Scaleheat shock protein 70Single nucleotide polymorphismSNPAcute angle-closure glaucomaAngle-closure glaucomaprimary angle-closure glaucoma
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Authors
Shi Song PhD, Fang Yao MBBS, Wai Kit DPhil, Li MMed, Jason C.S. FRCS (Edin), Shu Min MMed, Jian MMed, Hong PhD, Alvin L. FRCSI, Clement C. FRCS (Glas), Chi Pui DPhil, Li Jia PhD,