| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6200563 | Ophthalmology | 2014 | 8 Pages |
Abstract
Weekly injections of 30 μg of melphalan can result in a decreased ERG response, which is indicative of retinal toxicity. These findings are confirmed at an equivalent dose in rabbit eyes by ERG measurements and by histopathologic evidence of severe retinal damage. Systemic toxicity with intravitreal melphalan at these doses in humans or rabbits was not detected.
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Authors
Jasmine H. MD, Paula PhD, Emiliano BSc, MarÃa José PhD, Gustavo DVM, J. Oscar MD, PhD, Brian P. MD, Scott E. MD, Alejandro PhD, Guillermo L. MD, PhD, David H. MD,