Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6200742 | Ophthalmology | 2015 | 12 Pages |
Abstract
This study revealed 31 polymorphisms in 10 genes/loci that contribute to PCV susceptibility. Among them, ARMS2-HTRA1 also showed allelic diversity between PCV and nAMD. Our results confirm the gene variants that could affect the phenotypic expressions of PCV and nAMD.
Keywords
ICGACFHHWERPEARMS2HTRA1nAMDPolypoidal choroidal vasculopathyIndocyanine green angiographyretinal pigment epitheliumHardy–Weinberg equilibriumComplement factor Hage-related maculopathy susceptibility 2neovascular age-related macular degenerationconfidence intervalodds ratioPCV یا Pneumococcal conjugate vaccineSingle nucleotide polymorphismSNP
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Authors
Li MMed, Zhen MMed, Ke PhD, Shi Song PhD, Marten E. FRCOphth, PhD, Alvin L. FRCSI, Govindasamy MD, Chi Pui DPhil, Haoyu MD, PhD, Li Jia MRCSEd (Ophth), PhD,