| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6200867 | Ophthalmology | 2016 | 8 Pages |
Abstract
Delayed rod-mediated DA in older adults with normal macular health is associated with incident early AMD 3 years later, and thus is a functional biomarker for early disease. The biological relevance of this test is high, because it assesses translocation of vitamin A derivatives across the retinal pigment epithelium and Bruch's membrane, 2 tissues with prominent age- and AMD-related pathology.
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Authors
Cynthia PhD, Gerald PhD, Mark E. BS, Gregory R. PhD, Michael A. MD, Lanning B. MD, C. Douglas MD, Christine A. PhD,