| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6214792 | Otolaryngology - Head and Neck Surgery | 2010 | 8 Pages |
Abstract
Our findings point to acetaminophen, rather than hydrocodone, as the primary cytotoxic agent. Hydrocodone, however, may work synergistically with acetaminophen, increasing the damage to auditory cells. These findings are an important first step toward understanding the mechanism of acetaminophen/hydrocodone ototoxicity and may lead to future treatment strategies for hearing loss from ototoxic medications.
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Authors
Joshua G. MD, Gilda M. PhD, William M. MD, Frank M. MD, Federico PhD,