Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6214903 | Otolaryngology - Head and Neck Surgery | 2010 | 6 Pages |
Abstract
We showed an increased risk of presbycusis among white subjects carrying the GSTM1 and the GSTT1 null genotype and the NAT*6A mutant allele. Subjects with the GSTT1 null genotypes are almost three times more likely to develop presbycusis than those with the wild type. The GSTM1 null genotype was more prevalent in white Hispanics than in white non-Hispanics, but the GSTT1 and NAT2 polymorphisms were equally represented in the two groups.
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Authors
Anthony MD, Xiaomei Ouyang, Simon MD, Li Lin Du, Kimberly Hoang, Denise PhD, Xue Zhong MD, PhD,