| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6216062 | Human Pathology | 2013 | 5 Pages |
Abstract
SummaryAnaplastic lymphoma kinase-positive large B-cell lymphoma is a rare and aggressive B-cell lymphoma mostly associated with t(2:17) involving the clathrin gene at 17q23 and the anaplastic lymphoma kinase gene at 2p23. The characteristic immunophenotype includes a granular cytoplasmic anaplastic lymphoma kinase expression, CD20 negativity and the presence of plasma cell markers (CD138, VS38c, and CD38). We report a case with aberrant immunophenotype (CD138â, VS38câ, CD38+/â) and discuss the utility of other immunohistochemical markers in establishing a terminal B-cell differentiation.
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Authors
Francisco J. MD, Marcela MD, Ana MD, Karina MD, Ricardo MD, Diana PhD, Santiago MD, Carmen MD,