Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6222284 | The Journal of Pediatrics | 2014 | 13 Pages |
ObjectiveTo determine whether maternal mental health mediates the relationship between eczema or asthma symptoms and mental well-being in children.Study designAnalysis of 7250 children from the Avon Longitudinal Study of Parents and Children. Child mental well-being at 8Â years was measured by the Strengths and Difficulties Questionnaire. Binary outcomes were high 'internalizing' (anxious/depressive) and 'externalizing' (oppositional/hyperactive) problems (high was >90th percentile). Child rash and wheeze categories were 'none'; 'early onset transient' (infancy/preschool only); 'persistent' (infancy/preschool and at school age); and 'late onset' (school age only). Maternal anxiety and depression were reported during pregnancy and when child was 8Â years old.ResultsPersistent wheezing symptoms were associated with high externalizing (OR 1.74, 95% CI, 1.41-2.15) and internalizing (1.67, 1.35-2.06) problems compared with never wheeze. Maternal anxiety and depression, and disrupted child sleep, attenuated these associations. Persistent rash (externalizing: 1.74, 1.40-2.15; internalizing: 1.42, 1.16-1.74) and late onset rash (externalizing: 1.62, 1.17-2.25; internalizing: 1.46, 1.07-1.99) symptoms were associated with poorer mental well-being compared with no rash at any age. Maternal anxiety and depression, particularly when child was aged 8Â years rather than during pregnancy, accounted for the association with internalizing symptoms and partly for externalizing symptoms. Sleep disruption did not mediate the association.ConclusionsMaternal anxiety and depression may mediate the association between child rash and wheeze and child mental well-being.