| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6230235 | Journal of Affective Disorders | 2016 | 12 Pages |
Abstract
GDNF, IGF-1 and VEGF levels and their mRNA expression appear to be differentially altered in MDD patients compared to healthy individuals, indicating that these molecules might play an important role in the pathophysiology of depression and antidepressant action of therapeutic interventions.
Keywords
IGF-1TGF-βYears lost due to disabilityIGF-IRSNRIHDRSGDSGDNFYLDMDDDSMBDNFECsMajor depressive disorderbipolar disorderinsulin-like growth factor-1United States of AmericaUSABiomarkertransforming growth factor-βElectroconvulsive therapyICDDiagnostic and Statistical ManualInternational Classification of Diseasesbrain derived neurotrophic factorVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)Glial cell line-derived neurotrophic factorTrophic factorsCSFCerebrospinal fluidGeriatric Depression ScaleHamilton Depression Rating Scaleselective serotonin reuptake inhibitorsserotonin–norepinephrine reuptake inhibitorsSSRIGrowth hormoneTyrosine kinase receptor
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Authors
Ajaykumar N. Sharma, Bruno Fernando Borges da Costa e Silva, Jair C. Soares, André F. Carvalho, Joao Quevedo,