Risk of depressive disorders following sudden sensorineural hearing loss: A nationwide population-based retrospective cohort study

•Loss of an organ necessary to communicate with the outside world is a severe stressor.•National Health Insurance Research Database in Taiwan was used in this study.•Hazard ratio of depressive disorder of SSNHL and control cohort was calculated by a Cox model.•The result showed SSNHL increased the risk of developing depression.•Symptoms of depression should be evaluated in patients with SSNHL.

BackgroundSudden sensorineural hearing loss (SSNHL) occurs as an unexplained, rapid loss of hearing that can cause significant stress in the affected individual. This study aims to assess the risk of depressive disorders in SSNHL patients.MethodsFrom the National Health Insurance Research Database (NHIRD) in Taiwan, we identified new SSNHL patients diagnosed by an otolaryngologist between January 01, 2000, and December 31, 2008. A control group was composed of individuals who had never suffered from SSNHL. A total of 1717 SSNHL patients and 6868 individuals without SSNHL who were matched by sex, age and index date were followed until December 31, 2009, unless otherwise diagnosed with depressive disorders by a psychiatrist or deceased.ResultsThe results found that after adjusting for patients' age, sex, comorbidities, urbanization, and monthly income, SSNHL patients are 2.17 times more at risk (95% confidence interval [CI], 1.51-3.08, p<.001) for depressive disorders then control patients, especially in younger age groups (<60 years old).ConclusionsOur study indicated an increased risk of developing depressive disorders in patients with SSNHL, particularly for younger patients. Symptoms of depression should be regularly evaluated in patients with SSNHL.