| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6234154 | Journal of Affective Disorders | 2013 | 8 Pages |
Abstract
Significant independent effects of genotype and diagnosis on amygdala responsivity were revealed. The effects of genotype and diagnosis on amygdala connectivity showed a regional segregation, suggesting that 5-HTTLPR polymorphisms bias frontal-limbic connectivity while the development of depression involves more extensive neural disturbances. These findings point to the potential of connectivity maps as a diagnostic biomarker for depression.
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Authors
Sergi G. Costafreda, Peter McCann, Pascal Saker, James H. Cole, Sarah Cohen-Woods, Anne E. Farmer, Katherine J. Aitchison, Peter McGuffin, Cynthia H.Y. Fu,