| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6241358 | Respiratory Medicine | 2015 | 6 Pages |
Abstract
Asthma patients with persistent airflow obstruction present a distinct asthma phenotype, with significant differences in clinical, functional and inflammatory characteristics compared to patients without fixed airway obstruction. These patients present more often severe refractory asthma and require more intense treatment.
Keywords
FEV1severe refractory asthmaLTRAFRCFeNODLCOFVCATSICSBHRAsthmaCluster analysisleukotriene receptor antagonistsLong-acting β2-agonistsAirways inflammationAmerican Thoracic SocietyChronic obstructive pulmonary diseaseCOPDanalysis of varianceANOVAFraction of exhaled nitric oxideForced expiratory volume in 1 sSraLABAbody mass indexBMIGlobal Initiative for Asthmadiffusing capacity for carbon monoxideFunctional residual capacityforced vital capacityPhenotypeBronchial HyperresponsivenessInhaled corticosteroidsGINA
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Authors
Elissavet Konstantellou, Andriana I. Papaioannou, Stelios Loukides, George Patentalakis, Anastasia Papaporfyriou, Georgios Hillas, Spyros Papiris, Nikolaos Koulouris, Petros Bakakos, Konstantinos Kostikas,