Serum cytokine profiles of patients with interstitial lung disease associated with anti-CADM-140/MDA5 antibody positive amyopathic dermatomyositis

Article ID	Journal	Published Year	Pages	File Type
6241459	Respiratory Medicine	2015	7 Pages	PDF

Abstract

These results confirmed that anti-CADM-140/MDA5 antibody levels could predict outcomes of ADM-ILD. Relationship analyses suggested that CX3CL1 might be involved in the pathogenesis of anti-CADM-140/MDA5 antibody positive ADM-ILD.

Keywords

MDC PMX-DHP FMS-like tyrosine kinase-3 UIP MDA-5 IP-10 GM-CSF ADM MMF FGF-2 Tgf-α SSC FLT-3 EGF CX3CL1 RLR MIP-1α chemokine (C-X3-C motif) ligand 1 IPF MCP-1 ILD systemic sclerosis interferon IFN interleukin Interstitial lung disease transforming growth factor-α tumor necrosis factor-α computed tomography dermatomyositis amyopathic dermatomyositis Growth related oncogene Cytokine intravenous cyclophosphamide epidermal growth factor Granulocyte-colony stimulating factor Vascular endothelial growth factor Vascular Endothelial Growth Factor (VEGF)G-CSF TNF-α idiopathic pulmonary fibrosis granulocyte macrophage-colony stimulating factor Antibody Monocyte chemotactic protein-1 Macrophage inflammatory protein-1α Polymyositis Usual interstitial pneumonia melanoma differentiation-associated gene 5 Macrophage-derived chemokine Gro RIG-I-like receptor

Related Topics

Health Sciences Medicine and Dentistry Pulmonary and Respiratory Medicine

Serum cytokine profiles of patients with interstitial lung disease associated with anti-CADM-140/MDA5 antibody positive amyopathic dermatomyositis

Authors

Toshinori Takada, Ami Aoki, Katsuaki Asakawa, Takuro Sakagami, Hiroshi Moriyama, Ichiei Narita, Shinji Sato,