| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6242141 | Respiratory Medicine | 2013 | 8 Pages |
Abstract
Smoking asthmatics with a limited smoking history show a distinct pattern of airway pathology characterized by a bronchial infiltrate of CD8+ T cells and CD68+ macrophages, and epithelial remodelling resembling COPD-like features. This raises the hypothesis that early presence of CD8+ T cells contributes to disease progression in smoking asthmatics.
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Authors
A. Janneke Ravensberg, Annelies M. Slats, Sandra van Wetering, Kirsten Janssen, Simone van Wijngaarden, Ronald de Jeu, Klaus F. Rabe, Peter J. Sterk, Pieter S. Hiemstra,