Assessment of the Renal Corticomedullary 23Na Gradient Using Isotropic Data Sets

Assessment of renal corticomedullary [23Na] gradients using isotropic data sets with image reconstructions along the gradients is likely more accurate than measurements in the coronal plane. Because CSF [23Na] differs based on anatomic levels, such measures are useful as an internal reference only if region of interest placement is consistent. With this caveat in mind, normalization of renal to CSF 23Na signal provides a feasible, less cumbersome alternative to [23Na] calculations in intraindividual studies.