Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6244363 | European Journal of Radiology | 2012 | 7 Pages |
Abstract
The present study included 243 patients from seven studies. Results indicated a lack of significant heterogeneity for sensitivity and specificity (I2 < 50% and p > 0.05). The overall pooled estimates for sensitivity and specificity of FDG-PET or PET/CT scans in the detection of pelvic and/or paraaortic metastasis were 63.0% (95% CI, 48.7-75.7%) and 94.7% (95% CI, 90.4-97.4%), respectively. The positive likelihood ratio was 10.465 (95% CI, 5.646-19.396) and the negative likelihood ratio 0.399 (95% CI, 0.284-0.560). The AUC was 0.9533. The overall diagnostic accuracy (Q* index) was 89.5%. Conclusion The high positive likelihood value confirms the reliability of a positive FDG-PET or PET/CT to detect pelvic and/or paraaortic lymph nodes metastasis in patients with untreated endometrial cancer. FDG-PET or PET/CT may prove beneficial to surgeons when selecting appropriate patients on whom to perform lymphadenectomy.
Related Topics
Health Sciences
Medicine and Dentistry
Radiology and Imaging
Authors
Ming-Che Chang, Jin-Hua Chen, Ji-An Liang, Kuang-Tao Yang, Kai-Yuan Cheng, Chia-Hung Kao,