38th National Congress of the Italian Transplantation SocietyKidney transplantationEffect of Donor- and Recipient-Related Factors on Arterial Resistance Index After Kidney Transplant

•We investigated the effect of donor- and recipient-related factors on arterial resistance after kidney transplant.•We prospectively analyzed 90 patients who underwent RI assessment within the first month after the transplant.•HLA mismatch, donor age, and use of tacrolimus can influence recipient kidney vascular resistance.

BackgroundThe assessment of color Doppler resistance index (RI) of the intra-renal arteries has been shown to be a good predictor of short-term and long-term graft survival after kidney transplant. In this study, we investigated the influence of donor- and recipient-related factors on RI evaluated early after kidney transplant.MethodsWe prospectively analyzed 90 kidney transplant patients who underwent RI assessment within the first month after the transplant, subdivided into 2 groups according their RI values lower (group A) or higher (group B) than 0.646 (median value).ResultsPatients in group A had a lower human leukocyte antigen (HLA) mismatch number (3.3 ± 1 versus 3.9 ± 0.9, P = .007) and were significantly younger (42.8 ± 11 years versus 47.8 ± 11 years, P = .03) than patients in group B. All the others variables examined were not significantly different between the 2 groups. Multivariate logistic regression analysis confirmed that HLA mismatch number (P = .03) and recipient age (P = .03) are independent predictors of RI.ConclusionsOur data suggest that HLA mismatches and donor age can influence recipient kidney vascular resistance in the early period after transplantation.