Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6249011 | Transplantation Proceedings | 2011 | 6 Pages |
Abstract
Longer cold ischemic preservation time and less donor-recipient histocompatibility were associated with more advanced GVD in a rat heterotopic transplantation model, especially when there were multiple MHC mismatches as in ACI-Lewis allografts, but also occurred when there were differences in multiple non-MHC antigens as in the Lewis-F344 allografts. There was a lesser effect of longer cold ischemic time on GVD in the Lewis-Lewis syngeneic (isograft) group, suggesting that greater histocompatibility can mitigate the adverse effects of longer ischemic times.
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Authors
L.S.C. Czer, A.V. Wong, H. Soukiasian, S. Gallagher, M. De Robertis, A. Trento,