Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6249100 | Transplantation Proceedings | 2011 | 4 Pages |
Abstract
Mitochondrial respiratory chain disorders can cause acute liver failure in infants and children. Liver transplantation, however, has rarely been indicated for patients with mitochondrial respiratory chain disorders, because of the extrahepatic involvement. Herein we reported a case of acute liver failure with mitochondrial respiratory chain complex III deficiency treated by liver transplantation. At 2 years after transplantation, there were no extrahepatic manifestations. We suggest that mitochondrial disorders should be considered to be a cause of liver failure in infancy and that liver transplantation can be a life-saving treatment.
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Authors
I. Iwama, Y. Baba, S. Kagimoto, H. Kishimoto, M. Kasahara, K. Murayama, K. Shimizu,