Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6252650 | Journal of the American College of Surgeons | 2015 | 13 Pages |
Abstract
Obese patients receiving preinjury ACE/ARB therapy demonstrate post-injury MOF scores similar to nonobese patients; obese patients not receiving these medications have greater post-injury MOF. Leukocyte analysis demonstrates improved immune regulation. Modulation of the renin-angiotensin-aldosterone system pathway might represent a novel therapeutic target in severely injured obese patients.
Keywords
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Authors
Robert D. MD, FACS, Robert E. MD, Isaiah R. MD, PhD, Kelly RN, MSN, Stacey RN, MSN, Bradley D. MD, FACS, Grant V. MD, MPH, FACS,