| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6262138 | Brain Research Bulletin | 2012 | 6 Pages |
Abstract
⺠The terminal 5-HT2A receptors are involved in the regulation of 5-HT synthesis. ⺠A single dose of M100907 caused a significant decrease in the brain 5-HT synthesis. ⺠The M100907 treatment produces a large reduction of the 5-HT synthesis in the limbic structure.
Keywords
Tphα-[14C]methyl-l-tryptophanα-methyl-l-tryptophanM100907OBX5-hydroxytryptamine5-HT5-HT2A receptor antagonistAutoradiographyanalysis of varianceANOVAlumped constantVolume of distributionSelective serotonin reuptake inhibitorSSRISerotonin synthesis ratetryptophan hydroxylasehigh performance liquid chromatographyHPLC
Related Topics
Life Sciences
Neuroscience
Cellular and Molecular Neuroscience
Authors
Shu Hasegawa, Maraki Fikre-Merid, Mirko Diksic,