| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6264760 | Brain Research | 2011 | 9 Pages |
Abstract
⺠The animal model induced by prenatal exposure to valproic acid (VPA) has been proposed to study autism. ⺠We investigated behavioral and biochemical characteristics in rats after pre-natal exposure to VPA. ⺠VPA rats decreased: flexibility to change strategy; social approach; and place preference to conspecifics. ⺠These data contribute to the understanding of neurodevelopmental symptoms associated to the autism spectrum disorder.
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Authors
Victorio Bambini-Junior, Leticia Rodrigues, Guilherme Antônio Behr, José Cláudio Fonseca Moreira, Rudimar Riesgo, Carmem Gottfried,