Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6265864 | Brain Research | 2007 | 7 Pages |
Abstract
These results demonstrate that triple and quadruple combinations of these endogenous ligands caused more effective antihyperalgesia compared with double combinations. Accordingly, the doses of these substances could be further reduced, thus, reinforcing the view that complex activation and/or inhibition of different systems can be sufficiently effective in blocking nociception without adverse effects. Because all of these drugs had effects on various receptors and systems, the possible types of these interactions were discussed.
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Neuroscience (General)
Authors
Gyongyi Horvath, Gabriella Kekesi, Gabor Tuboly, Gyorgy Benedek,