| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6266699 | Current Opinion in Neurobiology | 2014 | 7 Pages |
â¢Hippocampal CA1 PV+ INs regulate PC spike timing and working memory.â¢Photoactivation of V1 PV+ INs increases orientation discrimination.â¢Disinhibition in auditory cortex is linked to fear learning and reinforcement.â¢Role of dendritic inhibition may be attenuated under anesthesia.
The majority of cellular diversity in the hippocampus and neocortex derives from a relatively small population of local inhibitory interneurons. Recent technological advances have facilitated the recording and manipulation of defined inhibitory cell classes in awake rodents, revealing new and surprising roles for these cells in local circuit function and behavior. Here we review recent progress in the analysis of inhibitory interneuron subtypes in neocortex and hippocampus during behavior, and suggest opportunities and considerations for extending this research program.
