| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6266892 | Current Opinion in Neurobiology | 2013 | 6 Pages |
Dyslexia is a polygenic developmental reading disorder characterized by an auditory/phonological deficit. Based on the latest genetic and neurophysiological studies, we propose a tentative model in which phonological deficits could arise from genetic anomalies of the cortical micro-architecture in the temporal lobe.
⺠Developmental dyslexia is a specific reading disability with a genetic component. ⺠Genetic variations associated with dyslexia disrupt neuronal migration and auditory processing. ⺠Anomalies of cortical micro-circuitry translate in abnormal cortical oscillations. ⺠Neural oscillations in auditory cortex facilitate processing of phonological units. ⺠Disrupted auditory cortical oscillations alter access to phonological representations.
