Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6268070 | Journal of Neuroscience Methods | 2015 | 8 Pages |
Abstract
We conclude (1) that correlation alone does not capture systematic differences (e.g. of hippocampal volumes), (2) calculation of ROI volumes with VBM8 gives measurements comparable to Freesurfer V5.0 when using the same ROI and (3) systematic and proportional differences are caused mainly by different definitions of anatomic boundaries and only to a lesser part by different segmentation strategies. This work underscores the importance of using method comparison techniques and demonstrates that even with high correlation coefficients, there can be still large differences in absolute volume.
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Authors
Oliver Grimm, Sebastian Pohlack, Raffaele Cacciaglia, Tobias Winkelmann, Michael M. Plichta, Traute Demirakca, Herta Flor,