Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6268446 | Journal of Neuroscience Methods | 2014 | 16 Pages |
Abstract
- Animal models of Tourette syndrome and other tic disorders (TD) are reviewed.
- TD models are based on genetic mutations and environmental interventions.
- TD models are validated across criteria of face, construct and predictive validity.
- Endophenotype testing is essential to enhance the translational value of TD models.
- TD models may assist in the identification of new therapeutic targets.
Related Topics
Life Sciences
Neuroscience
Neuroscience (General)
Authors
Sean C. Godar, Laura J. Mosher, Giuseppe Di Giovanni, Marco Bortolato,