Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6268585 | Journal of Neuroscience Methods | 2014 | 7 Pages |
Abstract
We demonstrate a straightforward and robust way to target AAV vector-mediated over-expression of genes to the peri-infarct region in a rat stroke model. This method will be useful for studying the action of specific proteins in peri-infarct region during the recovery process.
Keywords
PBSD/VL/MAAVMCAOCCAsTTCeGFPgene transferA/PMRImiddle cerebral artery occlusionFocal ischemiaFunctional recoveryTriphenyltetrazolium chlorideMagnetic resonance imagingcommon carotid arteriesanterior–posteriorphosphate-buffered saline solutionAnimal modelsAdeno-associated virusenhanced green fluorescent proteindorsal–ventral
Related Topics
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Neuroscience
Neuroscience (General)
Authors
Kert Mätlik, Usama Abo-Ramadan, Brandon K. Harvey, Urmas Arumäe, Mikko Airavaara,