Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6269068 | Journal of Neuroscience Methods | 2012 | 7 Pages |
Abstract
⺠We developed a lentiviral vector with human cytomegalovirus promoter to express nNOS. ⺠Lenti-nNOS infection up-regulates the expression of nNOS in vitro and in vivo. ⺠Lenti-nNOS infection showed time dependent increase in expression of nNOS. ⺠Lenti-nNOS can be used as a therapy for diseases known to have impaired nNOS expression.
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Neuroscience
Neuroscience (General)
Authors
Laura H.R. Leite, Neeru M. Sharma, Sangeeta Bafna, Hong Zheng, Cândido C. Coimbra, Kaushik P. Patel,