Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6269432 | Journal of Neuroscience Methods | 2013 | 6 Pages |
Abstract
⺠A murine chronic stress model based on two physical stressors is described. ⺠Plasmatic catecholamines and corticosterone levels are given. ⺠The model activates the HPA axis and corticosterone is an ideal metabolic stress biomarker. ⺠The combination of restraint and forced swimming does not provoke habituation. ⺠The model is useful for the study of chronic stress-related diseases.
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Authors
Edgar Oswaldo Zamora-González, Anne Santerre, Verónica Palomera-Avalos, Alberto Morales-Villagrán,