Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6269490 | Journal of Neuroscience Methods | 2012 | 11 Pages |
Abstract
⺠A third generation BMP7 lentiviral vector was developed and tested in several in vitro models. ⺠SMAD phosphorylation and neuronal differentiation assays were used to verify the bioactivity and functionality of the lentiviral-based BMP7. ⺠In vivo studies were performed to demonstrate the effectiveness of BMP7 infection in the mouse brain.
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Authors
David W. Chitty, Roger G. Tremblay, Maria Ribecco-Lutkiewicz, Julie Haukenfrers, Bogdan Zurakowski, Bernard Massie, Marianna Sikorska, Mahmud Bani-Yaghoub,